Towards further defining the proteome of mouse saliva.

ABSTRACT:

Background

Knowledge of the mouse salivary proteome is not well documented and as a result, very limited. Currently, several salivary proteins remain unidentified and for some others, their function yet to be determined. The goal of the present study is to utilize mass spectrometry analysis to widen our knowledge of mouse salivary proteins, and through extensive database searches, provide further insight into the array of proteins that can be found in saliva. A comprehensive mouse salivary proteome will also facilitate the development of mouse models to study specific biomarkers of many human diseases.

Results

Individual saliva samples were collected from male and female mice, and later pooled according to sex. Two pools of saliva from female mice (2 samples/pool) and 2 pool

SUBMITTER: Blanchard AA 

PROVIDER: S-EPMC4355469 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature