Analysis and prediction of defects in UV photo-initiated polymer microarrays.

ABSTRACT: Polymer microarrays are a key enabling technology for the discovery of novel materials. This technology can be further enhanced by expanding the combinatorial space represented on an array. However, not all materials are compatible with the microarray format and materials must be screened to assess their suitability with the microarray manufacturing methodology prior to their inclusion in a materials discovery investigation. In this study a library of materials expressed on the microarray format are assessed by light microscopy, atomic force microscopy and time-of-flight secondary ion mass spectrometry to identify compositions with defects that cause a polymer spot to exhibit surface properties significantly different from a smooth, round, chemically homogeneous 'normal' spot. It was demon

SUBMITTER: Hook AL 

PROVIDER: S-EPMC4357255 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature