Maastricht Delphi consensus on event definitions for classification of recurrence in breast cancer research.

ABSTRACT: In breast cancer studies, many different endpoints are used. Definitions are often not provided or vary between studies. For instance, "local recurrence" may include different components in similar studies. This limits transparency and comparability of results. This project aimed to reach consensus on the definitions of local event, second primary breast cancer, regional and distant event for breast cancer studies. The RAND-UCLA Appropriateness method (modified Delphi method) was used. A Consensus Group of international breast cancer experts was formed, including representatives of all involved clinical disciplines. Consensus was reached in two rounds of online questionnaires and one meeting. Twenty-four international breast cancer experts participated. Consensus was reached on 134 items i

SUBMITTER: Moossdorff M 

PROVIDER: S-EPMC4357796 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature