Luminescent ruthenium(II) complex bearing bipyridine and N-heterocyclic carbene-based C∧N∧C pincer ligand for live-cell imaging of endocytosis.

ABSTRACT: Luminescent ruthenium(II)-cyanide complex with N-heterocyclic carbene pincer ligand C(∧)N(∧)C = 2,6-bis(1-butylimidazol-2-ylidene)pyridine and 2,2'-bipyridine (bpy) shows minimal cytotoxicity to both human breast carcinoma cell (MCF-7) and human retinal pigmented epithelium cell (RPE) in a wide range of concentration (0.1-500 μM), and can be used for the luminescent imaging of endocytosis of the complex in these cells.

SUBMITTER: Tsui WK 

PROVIDER: S-EPMC4357851 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature