Transcriptome responses to heat stress in hypothalamus of a meat-type chicken.

ABSTRACT:

Background

Heat stress has resulted in great losses in poultry production. To address this issue, we systematically analyzed chicken hypothalamus transcriptome responses to thermal stress using a 44 k chicken Agilent microarray.

Methods

Hypothalamus samples were collected from a control group reared at 25°C, a heat-stress group treated at 34°C for 24 h, and a temperature-recovery group reared at 25°C for 24 h following a heat-stress treatment. We compared the expression profiles between each pair of the three groups using microarray data.

Results

A total of 1,967 probe sets were found to be differentially expressed in the three comparisons with P < 0.05 and a fold change (FC) higher than 1.5, and the genes were mainly involved in self-regulation and compensation requi

SUBMITTER: Sun H 

PROVIDER: S-EPMC4359534 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature