Nocturnal risk of gout attacks.

ABSTRACT:

Objective

Several plausible mechanisms and anecdotal descriptions suggest that gout attacks often occur at night, although there are no scientific data supporting this. We undertook this study to evaluate the hypothesis that gout attacks occur more frequently at night.

Methods

We conducted a case-crossover study to examine the risk of acute gout attacks in relation to the time of the day. Gout patients were prospectively recruited and followed up via the internet for 1 year. Participants were asked about the following information concerning their gout attacks: the date and hour of attack onset, symptoms and signs, medication use, and purported risk factors during the 24- and 48-hour periods prior to the gout attack. We calculated the odds ratios (ORs) of gout attacks (with 9

SUBMITTER: Choi HK 

PROVIDER: S-EPMC4360969 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature