Admixture and genetic diversity distribution patterns of non-recombining lineages of Native American ancestry in Colombian populations.

ABSTRACT: Genetic diversity of present American populations results from very complex demographic events involving different types and degrees of admixture. Through the analysis of lineage markers such as mtDNA and Y chromosome it is possible to recover the original Native American haplotypes, which remained identical since the admixture events due to the absence of recombination. However, the decrease in the effective population sizes and the consequent genetic drift effects suffered by these populations during the European colonization resulted in the loss or under-representation of a substantial fraction of the Native American lineages. In this study, we aim to clarify how the diversity and distribution of uniparental lineages vary with the different demographic characteristics (size, degree of i

SUBMITTER: Xavier C 

PROVIDER: S-EPMC4361580 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature