Genetic, chromosomal, and syndromic causes of neural tube defects.

ABSTRACT:

Objective

To ascertain the incidence, and describe the various forms of neural tube defects (NTDs) due to genetic, chromosomal, and syndromic causes.

Methods

We carried out a retrospective analysis of data retrieved from the medical records of newborn infants admitted to the Neonatal Intensive Care Unit with NTDs and their mothers spanning 14 years (1996-2009) at the Security Forces Hospital, Riyadh, Saudi Arabia. The cases were ascertained by a perinatologist, neonatologist, geneticist, radiologist, and neurologist. The literature was reviewed via a MEDLINE search. Only liveborn babies were included. Permission from the Educational Committee at the Security Forces Hospital was obtained prior to the collection of data.

Results

Out of 103 infants with NTDs admitted dur

SUBMITTER: Seidahmed MZ 

PROVIDER: S-EPMC4362101 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature