Assessment of relatedness between neurocan gene as bipolar disorder susceptibility locus and schizophrenia.

ABSTRACT: Large scale genetic association meta-analyses showed that neurocan (NCAN) gene polymorphism rs1064395 is susceptibility locus for bipolar disorder. These studies also included patients with bipolar disorder originated from Bosnia and Herzegovina. Followed by theory of shared genetic elements between bipolar disorder and schizophrenia susceptibility, other studies explored several genetic factors with schizophrenia vulnerability as well. In this work, authors investigated the association between previously confirmed bipolar disorder genetic risk factor- neurocan with schizophrenia in a population sample of Bosnia and Herzegovina. Ethical aspects of this research were assessed by Ethics Committee of Clinical Center University of Sarajevo. Blood samples for DNA extraction were taken from the

SUBMITTER: Oruc L 

PROVIDER: S-EPMC4362500 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature