Poor glycemic control is associated with reduced prostate specific antigen concentrations in men with type 1 diabetes.

ABSTRACT:

Purpose

Previous studies have revealed lower prostate specific antigen concentrations in men with type 2 diabetes, paralleling the reported lower prevalence of prostate cancer in diabetic men. Data are lacking on prostate specific antigen in men with type 1 diabetes whose insulin and obesity profiles differ from those with type 2 diabetes mellitus. In this study we examined the relationship between long-term glycemic control and prostate specific antigen in men with type 1 diabetes mellitus.

Materials and methods

Total prostate specific antigen was measured at one time in 639 men in the EDIC, the observational followup of participants in the DCCT. The relationship between DCCT/EDIC weighted mean hemoglobin A1c and log prostate specific antigen was assessed using linear regre

SUBMITTER: Sarma AV 

PROVIDER: S-EPMC4363040 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature