Offspring subcutaneous adipose markers are sensitive to the timing of maternal gestational weight gain.

ABSTRACT:

Background

Excessive maternal weight gain during pregnancy impacts on offspring health. This study focused on the timing of maternal gestational weight gain, using a porcine model with mothers of normal pre-pregnancy weight.

Methods

Trial design ensured the trajectory of maternal gestational weight gain differed across treatments in early, mid and late gestation. Diet composition did not differ. On day 25 gestation, sows were assigned to one of five treatments: Control sows received a standard gestation diet of 2.3 kg/day (30 MJ DE/day) from early to late gestation (day 25-110 gestation). E sows received 4.6 kg food/day in early gestation (day 25-50 gestation). M sows doubled their food intake in mid gestation (day 50-80 gestation). EM sows doubled their food intake during b

SUBMITTER: Giblin L 

PROVIDER: S-EPMC4363193 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature