Early-life mold and tree sensitivity is associated with allergic eosinophilic rhinitis at 4 years of age.

ABSTRACT:

Background

Nasal eosinophils are a biomarker for allergic rhinitis (AR) and are associated with increased symptom severity.

Objective

To identify predictors of allergic eosinophilic rhinitis (AER) in early childhood in children at higher risk for chronic allergic respiratory disorders.

Methods

In the Cincinnati Childhood Allergy and Air Pollution Study, infants born to aeroallergen-sensitized and symptomatic parents were examined and underwent skin prick testing (SPT) annually to 15 aeroallergens from 1 to 4 years of age. Wheal circumferences were traced and scanned and areas were determined by computer planimetry. At 4 years, AER was defined as (1) at least 1 positive aeroallergen SPT result, (2) presence of sneezing and runny nose without a cold or influenza, and (3

SUBMITTER: Codispoti CD 

PROVIDER: S-EPMC4363311 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature