Mitogenomes from The 1000 Genome Project reveal new Near Eastern features in present-day Tuscans.

ABSTRACT:

Background

Genetic analyses have recently been carried out on present-day Tuscans (Central Italy) in order to investigate their presumable recent Near East ancestry in connection with the long-standing debate on the origins of the Etruscan civilization. We retrieved mitogenomes and genome-wide SNP data from 110 Tuscans analyzed within the context of The 1000 Genome Project. For phylogeographic and evolutionary analysis we made use of a large worldwide database of entire mitogenomes (>26,000) and partial control region sequences (>180,000).

Results

Different analyses reveal the presence of typical Near East haplotypes in Tuscans representing isolated members of various mtDNA phylogenetic branches. As a whole, the Near East component in Tuscan mitogenomes can be estimated at a

SUBMITTER: Gomez-Carballa A 

PROVIDER: S-EPMC4365045 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature