Variola virus-specific diagnostic assays: characterization, sensitivity, and specificity.

ABSTRACT: A public health response relies upon rapid and reliable confirmation of disease by diagnostic assays. Here, we detail the design and validation of two variola virus-specific real-time PCR assays, since previous assays cross-reacted with newly identified cowpox viruses. The assay specificity must continually be reassessed as other closely related viruses are identified.

SUBMITTER: Kondas AV 

PROVIDER: S-EPMC4365196 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature