Molecular hazard identification of non-O157 Shiga toxin-producing Escherichia coli (STEC).

ABSTRACT: The complexity regarding Shiga toxin-producing Escherichia coli (STEC) in food safety enforcement as well as clinical care primarily relates to the current inability of an accurate risk assessment of individual strains due to the large variety in serotype and genetic content associated with (severe) disease. In order to classify the clinical and/or epidemic potential of a STEC isolate at an early stage it is crucial to identify virulence characteristics of putative pathogens from genomic information, which is referred to as 'predictive hazard identification'. This study aimed at identifying associations between virulence factors, phylogenetic groups, isolation sources and seropathotypes. Most non-O157 STEC in the Netherlands belong to phylogroup B1 and are characterized by the presence of

SUBMITTER: Franz E 

PROVIDER: S-EPMC4366395 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature