Concise review: workshop review: understanding and assessing the risks of stem cell-based therapies.

ABSTRACT: The field of stem cell therapeutics is moving ever closer to widespread application in the clinic. However, despite the undoubted potential held by these therapies, the balance between risk and benefit remains difficult to predict. As in any new field, a lack of previous application in man and gaps in the underlying science mean that regulators and investigators continue to look for a balance between minimizing potential risk and ensuring therapies are not needlessly kept from patients. Here, we attempt to identify the important safety issues, assessing the current advances in scientific knowledge and how they may translate to clinical therapeutic strategies in the identification and management of these risks. We also investigate the tools and techniques currently available to researchers

SUBMITTER: Heslop JA 

PROVIDER: S-EPMC4367503 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature