Different contribution of BRINP3 gene in chronic periodontitis and peri-implantitis: a cross-sectional study.

ABSTRACT:

Background

Peri-implantitis is a chronic inflammation, resulting in loss of supporting bone around implants. Chronic periodontitis is a risk indicator for implant failure. Both diseases have a common etiology regarding inflammatory destructive response. BRINP3 gene is associated with aggressive periodontitis. However, is still unclear if chronic periodontitis and peri-implantitis have the same genetic background. The aim of this work was to investigate the association between BRINP3 genetic variation (rs1342913 and rs1935881) and expression and susceptibility to both diseases.

Methods

Periodontal and peri-implant examinations were performed in 215 subjects, divided into: healthy (without chronic periodontitis and peri-implantitis, n = 93); diseased (with chronic periodontiti

SUBMITTER: Casado PL 

PROVIDER: S-EPMC4367924 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature