Infections and obstetric outcomes in opioid-dependent pregnant women maintained on methadone or buprenorphine.

ABSTRACT:

Aims

To characterize infections and compare obstetric outcomes in opioid-dependent pregnant women who participated in a randomized clinical trial comparing agonist medications, methadone and buprenorphine.

Design

Incidence of infections was identified as part of the screening medical assessment. As part of a planned secondary analysis, analysis of variance and polytomous logistic regressions were conducted on obstetric outcome variables using treatment randomization condition (maternal maintenance with either methadone or buprenorphine) as the predictor variable, controlling for differences between study sites.

Setting

Six United States sites and one European site that provided comprehensive treatment to opioid-dependent pregnant women.

Participants

Pregnant op

SUBMITTER: Holbrook AM 

PROVIDER: S-EPMC4368056 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature