Risk factors for chronic rhinosinusitis.

ABSTRACT:

Purpose of review

To review the recent literature on risk factors for chronic rhinosinusitis (CRS) with an emphasis on genetic, comorbid diseases and environmental factors associated with CRS. Through identifying potential risk factors for CRS, we aim to glean insights into the underlying pathogenic mechanisms essential for developing effective therapeutic strategies.

Recent findings

Recent findings demonstrate that genetics and comorbid medical conditions including airway diseases, gastroesophageal reflux disease, inflammatory and autoimmune diseases, and various demographic and environmental factors are associated with having a CRS diagnosis. Limitations of current studies include variable application of disease definitions, lack of prospective longitudinal studies and a d

SUBMITTER: Min JY 

PROVIDER: S-EPMC4368058 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature