Simultaneous fat saturation and magnetization transfer contrast imaging with steady-state incoherent sequences.

ABSTRACT:

Purpose

This work combines an n-dimensional fat sat(uration) radiofrequency (RF) pulse with steady-state incoherent (SSI) pulse sequences, e.g., spoiled gradient-echo sequence, to simultaneously produce B0 insensitive fat suppression and magnetization transfer (MT) contrast. This pulse is then referred to as "fat sat and MT contrast pulse."

Theory

We discuss the features of the fat sat and MT contrast pulse and the MT sensitivities of the SSI sequences when combining with fat sat. Moreover, we also introduce an adapted RF spoiling scheme for SSI sequences with fat sat.

Methods

Simulations and phantom experiments were conducted to demonstrate the adapted RF spoiling. Fat suppression and MT effects are shown in 3T phantom experiments and in vivo experiments, including b

SUBMITTER: Zhao F 

PROVIDER: S-EPMC4369465 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature