Hyperlipidemia in early adulthood increases long-term risk of coronary heart disease.

ABSTRACT:

Background

Many young adults with moderate hyperlipidemia do not meet statin treatment criteria under the new American Heart Association/American College of Cardiology cholesterol guidelines because they focus on 10-year cardiovascular risk. We evaluated the association between years of exposure to hypercholesterolemia in early adulthood and future coronary heart disease (CHD) risk.

Methods and results

We examined Framingham Offspring Cohort data to identify adults without incident cardiovascular disease to 55 years of age (n=1478), and explored the association between duration of moderate hyperlipidemia (non-high-density lipoprotein cholesterol ≥ 160 mg/dL) in early adulthood and subsequent CHD. At median 15-year follow-up, CHD rates were significantly elevated among adults

SUBMITTER: Navar-Boggan AM 

PROVIDER: S-EPMC4370230 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature