Calcium acetate or calcium carbonate for hyperphosphatemia of hemodialysis patients: a meta-analysis.

ABSTRACT:

Background

High levels of serum phosphorus both at baseline and during follow-up are associated with increased mortality in dialysis patients, and administration of phosphate binders was independently associated with improved survival among hemodialysis population. Calcium-based phosphate binders are the most commonly used phosphate binders in developing countries for their relatively low costs.

Objectives

To compare the efficacy and safety between calcium carbonate and calcium acetate in the treatment of hyperphosphatemia in hemodialysis patients.

Methods

PubMed, EMBASE, Cochrane Library, Google scholar and Chinese databases (Wanfang, Weipu, National Knowledge Infrastructure of China) were searched for relevant studies published before March 2014. Reference lists of

SUBMITTER: Wang Y 

PROVIDER: S-EPMC4370772 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature