Sleep duration and risk of fatal and nonfatal stroke: a prospective study and meta-analysis.

ABSTRACT:

Objective

To study the association between sleep duration and stroke incidence in a British population and to synthesize our findings with published results through a meta-analysis.

Methods

The prospective study included 9,692 stroke-free participants aged 42-81 years from the European Prospective Investigation into Cancer-Norfolk cohort. Participants reported sleep duration in 1998-2000 and 2002-2004, and all stroke cases were recorded until March 31, 2009. For the meta-analysis, we searched Ovid Medline, EMBASE, and the Cochrane Library for prospective studies published until May 2014, and pooled effect estimates using a weighted random-effect model.

Results

After 9.5 years of follow-up, 346 cases of stroke occurred. Long sleep was significantly associated with an i

SUBMITTER: Leng Y 

PROVIDER: S-EPMC4371404 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature