ATG18 and FAB1 are involved in dehydration stress tolerance in Saccharomyces cerevisiae.

ABSTRACT: Recently, different dehydration-based technologies have been evaluated for the purpose of cell and tissue preservation. Although some early results have been promising, they have not satisfied the requirements for large-scale applications. The long experience of using quantitative trait loci (QTLs) with the yeast Saccharomyces cerevisiae has proven to be a good model organism for studying the link between complex phenotypes and DNA variations. Here, we use QTL analysis as a tool for identifying the specific yeast traits involved in dehydration stress tolerance. Three hybrids obtained from stable haploids and sequenced in the Saccharomyces Genome Resequencing Project showed intermediate dehydration tolerance in most cases. The dehydration resistance trait of 96 segregants from each hybrid w

SUBMITTER: Lopez-Martinez G 

PROVIDER: S-EPMC4372426 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature