Hypertriglyceridemia is a potential preoperative predictor for biochemical recurrence after radical prostatectomy.

ABSTRACT:

Objectives

Many previous studies have suggested that the outcome of prostate cancer (PCa) may be closely related to abnormal lipid metabolism. Therefore, in this study, we evaluated the preoperative lipid profiles of patients with clinically localized prostate cancer (PCa) who underwent radical prostatectomy (RP), with particular emphasis on the relationship between these profiles and biochemical recurrence (BCR).

Patients and methods

We evaluated 715 consecutive men with clinically localized PCa who underwent RP at our institution between January 2011 and December 2013. We defined hypertriglyceridemia as a fasting serum triglyceride (TG) level greater than 200 mg/dL. We used the Kaplan-Meier method to predict BCR-free survival and applied the log-rank test to determine the

SUBMITTER: Kang M 

PROVIDER: S-EPMC4372604 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature