Novel equations better predict lung age: a retrospective analysis using two cohorts of participants with medical check-up examinations in Japan.

ABSTRACT:

Background

The lung age equations developed by the Japanese Respiratory Society encounter several problems when being applied in a clinical setting.

Aims

To establish novel spirometry-derived lung age (SDL age) equations using data from a large number of Japanese healthy never-smokers with normal spirometric measurements and normal body mass indices (BMIs).

Methods

The participants had undergone medical check-ups at the Center for Preventive Medicine of St Luke's International Hospital between 2004 and 2012. A total of 15,238 Japanese participants (5,499 males and 9,739 females) were chosen for the discovery cohort. The other independent 2,079 individuals were selected for the validation cohort. The original method of Morris and Temple was applied to the discovery coh

SUBMITTER: Ishida Y 

PROVIDER: S-EPMC4373493 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature