Randomized trial of drain antisepsis after mastectomy and immediate prosthetic breast reconstruction.

ABSTRACT:

Background

In this 2-site randomized trial, we investigated the effect of antiseptic drain care on bacterial colonization of surgical drains and infection after immediate prosthetic breast reconstruction.

Methods

With IRB approval, we randomized patients undergoing bilateral mastectomy and reconstruction to drain antisepsis (treatment) for one side, with standard drain care (control) for the other. Antisepsis care included both: chlorhexidine disc dressing at drain exit site(s) and irrigation of drain bulbs twice daily with dilute sodium hypochlorite solution. Cultures were obtained from bulb fluid at 1 week and at drain removal, and from the subcutaneous drain tubing at removal. Positive cultures were defined as ≥1+ growth for fluid and >50 CFU for tubing.

Results

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SUBMITTER: Degnim AC 

PROVIDER: S-EPMC4373621 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature