Characterizing heterogeneity in children with and without ADHD based on reward system connectivity.

ABSTRACT: One potential obstacle limiting our ability to clarify ADHD etiology is the heterogeneity within the disorder, as well as in typical samples. In this study, we utilized a community detection approach on 106 children with and without ADHD (aged 7-12 years), in order to identify potential subgroups of participants based on the connectivity of the reward system. Children with ADHD were compared to typically developing children within each identified community, aiming to find the community-specific ADHD characteristics. Furthermore, to assess how the organization in subgroups relates to behavior, we evaluated delay-discounting gradient and impulsivity-related temperament traits within each community. We found that discrete subgroups were identified that characterized distinct connectivity prof

SUBMITTER: Costa Dias TG 

PROVIDER: S-EPMC4373624 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature