Sensory and motor peripheral nerve function and longitudinal changes in quadriceps strength.

ABSTRACT:

Background

Poor peripheral nerve function is common in older adults and may be a risk factor for strength decline, although this has not been assessed longitudinally.

Methods

We assessed whether sensorimotor peripheral nerve function predicts strength longitudinally in 1,830 participants (age = 76.3 ± 2.8, body mass index = 27.2 ± 4.6kg/m(2), strength = 96.3 ± 34.7 Nm, 51.0% female, 34.8% black) from the Health ABC study. Isokinetic quadriceps strength was measured semiannually over 6 years. Peroneal motor nerve conduction amplitude and velocity were recorded. Sensory nerve function was assessed with 10-g and 1.4-g monofilaments and average vibration detection threshold at the toe. Lower-extremity neuropathy symptoms were self-reported.

Results

Worse vibration detecti

SUBMITTER: Ward RE 

PROVIDER: S-EPMC4375416 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature