Ontology highlight
ABSTRACT:
SUBMITTER: Bortolotti F
PROVIDER: S-EPMC4375942 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Bortolotti Francesca F Ukovich Laura L Razban Vahid V Martinelli Valentina V Ruozi Giulia G Pelos Barbara B Dore Franca F Giacca Mauro M Zacchigna Serena S
Stem cell reports 20150205 3
Over the last several years, mesenchymal stromal cells (MSCs) have been isolated from different tissues following a variety of different procedures. Here, we comparatively assess the ex vivo and in vivo properties of MSCs isolated from either adipose tissue or bone marrow by different purification protocols. After MSC transplantation into a mouse model of hindlimb ischemia, clinical and histological analysis revealed that bone marrow MSCs purified on adhesive substrates exerted the best therapeu ...[more]