Use of perioperative hydroxyethyl starch 6% and albumin 5% in elective joint arthroplasty and association with adverse outcomes: a retrospective population based analysis.

ABSTRACT:

Objective

To determine whether the perioperative use of hydroxyethyl starch 6% and albumin 5% in elective joint arthroplasties are associated with an increased risk for perioperative complications.

Design

Retrospective cohort study of population based data between 2006 and 2013.

Setting

Data from 510 different hospitals across the United States participating in the Premier Perspective database.

Participants

1,051,441 patients undergoing elective total hip and knee arthroplasties.

Exposures

Perioperative fluid resuscitation with hydroxyethyl starch 6% or albumin 5%, or neither.

Main outcome measures

Acute renal failure and thromboembolic, cardiac, and pulmonary complications.

Results

Compared with patients who received neither colloid, perio

SUBMITTER: Opperer M 

PROVIDER: S-EPMC4376265 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature