Neonatal effect of remifentanil in general anaesthesia for caesarean section: a randomized trial.

ABSTRACT:

Background

Remifentanil has been suggested for its short duration of action to replace standard opioids for induction of general anaesthesia in caesarean section. While the stabilizing effect of remifentanil on maternal circulation has been confirmed, its effect on postnatal adaptation remains unclear, as currently published studies are not powered sufficiently to detect any clinical effect of remifentanil on the newborn.

Methods

Using a double-blinded randomized design, a total of 151 parturients undergoing caesarean delivery under general anaesthesia were randomized into two groups--76 patients received a bolus of remifentanil prior to induction, while 75 patients were assigned to the control group. Remifentanil 1 μg/kg was administered 30 seconds before the standard induc

SUBMITTER: Noskova P 

PROVIDER: S-EPMC4377196 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature