Functional MRI neurofeedback training on connectivity between two regions induces long-lasting changes in intrinsic functional network.

ABSTRACT: Motor or perceptual learning is known to influence functional connectivity between brain regions and induce short-term changes in the intrinsic functional networks revealed as correlations in slow blood-oxygen-level dependent (BOLD) signal fluctuations. However, no cause-and-effect relationship has been elucidated between a specific change in connectivity and a long-term change in global networks. Here, we examine the hypothesis that functional connectivity (i.e., temporal correlation between two regions) is increased and preserved for a long time when two regions are simultaneously activated or deactivated. Using the connectivity-neurofeedback training paradigm, subjects successfully learned to increase the correlation of activity between the lateral parietal and primary motor areas, regi

SUBMITTER: Megumi F 

PROVIDER: S-EPMC4377493 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature