Motif mismatches in microsatellites: insights from genome-wide investigation among 20 insect species.

ABSTRACT: We present a detailed genome-wide comparative study of motif mismatches of microsatellites among 20 insect species representing five taxonomic orders. The results show that varying proportions (∼15-46%) of microsatellites identified in these species are imperfect in motif structure, and that they also vary in chromosomal distribution within genomes. It was observed that the genomic abundance of imperfect repeats is significantly associated with the length and number of motif mismatches of microsatellites. Furthermore, microsatellites with a higher number of mismatches tend to have lower abundance in the genome, suggesting that sequence heterogeneity of repeat motifs is a key determinant of genomic abundance of microsatellites. This relationship seems to be a general feature of microsatelli

SUBMITTER: Behura SK 

PROVIDER: S-EPMC4379975 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature