Relationship of physical function and quality of life among persons aging with HIV infection.

ABSTRACT:

Objective

Physical function impairments are seen among aging, HIV-infected persons on effective antiretroviral therapy (ART). The impact of physical function impairments on health-related quality of life (QoL) during ART is unknown.

Design

This was a cross-sectional study including 359 HIV-infected patients, aged 45-65 years, on ART for more than 6 months.

Methods

Patients completed the SF-36 QoL questionnaire, 400-m walk, 5-time chair rise, and grip strength. HIV-associated mortality risk was calculated using the Veterans Aging Cohort Study (VACS) Index. Physical function, physical activity (> 500 versus ≤ 500 kcal/week), and VACS scores were used to estimate QoL in multivariable linear regression.

Results

For every 1 m/s increase in gait speed, we saw an esti

SUBMITTER: Erlandson KM 

PROVIDER: S-EPMC4380343 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature