A novel model to predict esophageal varices in patients with compensated cirrhosis using acoustic radiation force impulse elastography.

ABSTRACT:

Background & aims

Few noninvasive methods can accurately identify esophageal varices (EVs) in patients with compensated cirrhosis. We developed and validated a novel, acoustic radiation force impulse (ARFI) elastography-based prediction model for high-risk EVs (HEVs) in patients with compensated cirrhosis.

Methods

A total of 143 patients with compensated cirrhosis between February, 2010 and February, 2013 (training set) and 148 between June, 2010 and May, 2013 (validation set) who underwent ARFI elastography and endoscopy were prospectively recruited. Independent predictors of HEVs were used to construct a prediction model.

Results

Based on multivariate analysis, we developed two new statistical models, a varices risk score and ARFI-spleen diameter-to-platelet ratio s

SUBMITTER: Park Y 

PROVIDER: S-EPMC4380431 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature