Ontology highlight
ABSTRACT:
SUBMITTER: Onengut-Gumuscu S
PROVIDER: S-EPMC4380767 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Nature genetics 20150309 4
Genetic studies of type 1 diabetes (T1D) have identified 50 susceptibility regions, finding major pathways contributing to risk, with some loci shared across immune disorders. To make genetic comparisons across autoimmune disorders as informative as possible, a dense genotyping array, the Immunochip, was developed, from which we identified four new T1D-associated regions (P < 5 × 10(-8)). A comparative analysis with 15 immune diseases showed that T1D is more similar genetically to other autoanti ...[more]