Prospective assessment of the prevalence of pelvic, paraaortic and high paraaortic lymph node metastasis in endometrial cancer.

ABSTRACT:

Objective

To prospectively define the prevalence of lymph node metastasis (LNM) in at risk endometrial cancer (EC).

Methods

From 2004 to 2008, frozen section based Mayo Criteria prospectively identified patients "not at-risk" of LNM (30% EC population; grade I/II, <50% myometrial invasion and tumor diameter ≤ 2 cm) where lymphadenectomy was not recommended. The remaining 70% EC cohort was considered "at-risk" of LNM; where a systematic pelvic and infrarenal paraaortic lymphadenectomy was recommended. Patients were prospectively followed. The area between renal vein and inferior mesenteric artery (IMA) was labeled as high paraaortic area. For calculating the prevalence of LNM in high paraaortic area, the denominator was the population with known anatomic location of nodal tis

SUBMITTER: Kumar S 

PROVIDER: S-EPMC4381544 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature