Novel disease susceptibility factors for fungal necrotrophic pathogens in Arabidopsis.

ABSTRACT: Host cells use an intricate signaling system to respond to invasions by pathogenic microorganisms. Although several signaling components of disease resistance against necrotrophic fungal pathogens have been identified, our understanding for how molecular components and host processes contribute to plant disease susceptibility is rather sparse. Here, we identified four transcription factors (TFs) from Arabidopsis that limit pathogen spread. Arabidopsis mutants defective in any of these TFs displayed increased disease susceptibility to Botrytis cinerea and Plectosphaerella cucumerina, and a general activation of non-immune host processes that contribute to plant disease susceptibility. Transcriptome analyses revealed that the mutants share a common transcriptional signature of 77 up-regulate

SUBMITTER: Dobon A 

PROVIDER: S-EPMC4382300 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature