GeneFriends: a human RNA-seq-based gene and transcript co-expression database.

ABSTRACT: Co-expression networks have proven effective at assigning putative functions to genes based on the functional annotation of their co-expressed partners, in candidate gene prioritization studies and in improving our understanding of regulatory networks. The growing number of genome resequencing efforts and genome-wide association studies often identify loci containing novel genes and there is a need to infer their functions and interaction partners. To facilitate this we have expanded GeneFriends, an online database that allows users to identify co-expressed genes with one or more user-defined genes. This expansion entails an RNA-seq-based co-expression map that includes genes and transcripts that are not present in the microarray-based co-expression maps, including over 10,000 non-coding R

SUBMITTER: van Dam S 

PROVIDER: S-EPMC4383890 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature