MiCroKiTS 4.0: a database of midbody, centrosome, kinetochore, telomere and spindle.

ABSTRACT: We reported an updated database of MiCroKiTS 4.0 (http://microkit.biocuckoo.org) for proteins temporally and spatially localized in distinct subcellular positions including midbody, centrosome, kinetochore, telomere and mitotic spindle during cell division/mitosis. The database was updated from our previously developed database of MiCroKit 3.0, which contained 1489 proteins mostly forming super-complexes at midbody, centrosome and kinetochore from seven eukaryotes. Since the telomere and spindle apparatus are critical for cell division, the proteins localized at the two positions were also integrated. From the scientific literature, we curated 1872 experimentally identified proteins which at least locate in one of the five positions from eight species. Then the ortholog detection was perfo

SUBMITTER: Huang Z 

PROVIDER: S-EPMC4383938 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature