Multi-institutional feasibility study of a fast patient localization method in total marrow irradiation with helical tomotherapy: a global health initiative by the international consortium of total marrow irradiation.

ABSTRACT:

Purpose

To develop, characterize, and implement a fast patient localization method for total marrow irradiation.

Methods and materials

Topographic images were acquired using megavoltage computed tomography (MVCT) detector data by delivering static orthogonal beams while the couch traversed through the gantry. Geometric and detector response corrections were performed to generate a megavoltage topogram (MVtopo). We also generated kilovoltage topograms (kVtopo) from the projection data of 3-dimensional CT images to reproduce the same geometry as helical tomotherapy. The MVtopo imaging dose and the optimal image acquisition parameters were investigated. A multi-institutional phantom study was performed to verify the image registration uncertainty. Forty-five MVtopo images were

SUBMITTER: Takahashi Y 

PROVIDER: S-EPMC4385424 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature