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Subsistence strategies in traditional societies distinguish gut microbiomes.


ABSTRACT: Recent studies suggest that gut microbiomes of urban-industrialized societies are different from those of traditional peoples. Here we examine the relationship between lifeways and gut microbiota through taxonomic and functional potential characterization of faecal samples from hunter-gatherer and traditional agriculturalist communities in Peru and an urban-industrialized community from the US. We find that in addition to taxonomic and metabolic differences between urban and traditional lifestyles, hunter-gatherers form a distinct sub-group among traditional peoples. As observed in previous studies, we find that Treponema are characteristic of traditional gut microbiomes. Moreover, through genome reconstruction (2.2-2.5 MB, coverage depth × 26-513) and functional potential characterization

SUBMITTER: Obregon-Tito AJ 

PROVIDER: S-EPMC4386023 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature