Relapsing-remitting multiple sclerosis: patterns of response to disease-modifying therapies and associated factors: a national survey.

ABSTRACT:

Introduction

Current treatments for relapsing-remitting multiple sclerosis (RRMS) are only partially effective. The objective of this study was to characterize treatment response in RRMS patients in Portugal to 12-month therapy with first-line disease-modifying therapies.

Methods

In this retrospective study, neurologists at participating centers completed survey questionnaires using records of patients with RRMS who had received first-line treatment with one of five European Medicine Agency-approved agents in the 12 months prior to inclusion in the survey. Sub-optimal responders included patients treated for at least 1 year, and who had ≥1 relapse(s) or an increase of 1.5 points on the Expanded Disability Status Scale (EDSS; if baseline EDSS was 0) or an increase of ≥0.5 poi

SUBMITTER: Sa MJ 

PROVIDER: S-EPMC4386429 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature