"Skeletal muscle function deficit" in a nationally representative British birth cohort in early old age.

ABSTRACT:

Background

Recommendations for identifying age-related muscle dysfunction have recently been published. We aimed to compare definitions for clinically relevant weakness and low lean mass proposed by the Foundation for the National Institutes of Health (FNIH) Sarcopenia project with the definition of sarcopenia proposed by the European Working Group on Sarcopenia in Older People (EWGSOP).

Methods

A total of 1566 men and women from a British birth cohort had measures of appendicular lean mass, grip strength and timed up, and go speed at ages 60-64. Prevalence of low lean mass, weakness and slowness, identified using the FNIH and EWGSOP recommendations were estimated and compared: using kappa statistics and; by testing cross-sectional associations of both definitions of low lea

SUBMITTER: Cooper R 

PROVIDER: S-EPMC4386990 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature