Association of menopause age and N-terminal pro brain natriuretic peptide: the Multi-Ethnic Study of Atherosclerosis.

ABSTRACT:

Objective

Menopause age can affect the risk of developing cardiovascular disease (CVD). The purpose of this study was to investigate the associations of early menopause (menopause occurring before age 45 y) and menopause age with N-terminal pro brain natriuretic peptide (NT-proBNP), a potential risk marker of CVD and heart failure.

Methods

Our cross-sectional study included 2,275 postmenopausal women, aged 45 to 85 years and without clinical CVD (2000-2002), from the Multi-Ethnic Study of Atherosclerosis. Participants were classified as having or not having early menopause. NT-proBNP was log-transformed. Multivariable linear regression was used for analysis.

Results

Five hundred sixty-one women had early menopause. The median (25th-75th percentiles) NT-proBNP value wa

SUBMITTER: Ebong IA 

PROVIDER: S-EPMC4387119 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature