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Proteo-lipobeads for the oriented encapsulation of membrane proteins.


ABSTRACT: As a surrogate of live cells, proteo-lipobeads are presented, encapsulating functional membrane proteins in a strict orientation into a lipid bilayer. Assays can be performed just as on live cells, for example using fluorescence measurements. As a proof of concept, we have demonstrated proton transport through cytochrome c oxidase.

SUBMITTER: Frank P 

PROVIDER: S-EPMC4387127 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature