Evolutionary history of Leishmania killicki (synonymous Leishmania tropica) and taxonomic implications.

ABSTRACT:

Background

The taxonomic status of Leishmania (L.) killicki, a parasite that causes chronic cutaneous leishmaniasis, is not well defined yet. Indeed, some researchers suggested that this taxon could be included in the L. tropica complex, whereas others considered it as a distinct phylogenetic complex. To try to solve this taxonomic issue we carried out a detailed study on the evolutionary history of L. killicki relative to L. tropica.

Methods

Thirty-five L. killicki and 25 L. tropica strains isolated from humans and originating from several countries were characterized using the MultiLocus Enzyme Electrophoresis (MLEE) and the MultiLocus Sequence Typing (MLST) approaches.

Results

The results of the genetic and phylogenetic analyses strongly support the hypothesis that

SUBMITTER: Chaara D 

PROVIDER: S-EPMC4387592 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature