Independent impact of gout on the risk of diabetes mellitus among women and men: a population-based, BMI-matched cohort study.

ABSTRACT:

Objective

Evidence on the potential independent impact of gout on the risk of diabetes is limited to a single study of men with a high cardiovascular risk profile. Our objective was to examine this relation in the general population, particularly among women.

Methods

We conducted a sex-stratified matched cohort study using data from The Health Improvement Network (THIN), an electronic medical records database representative of the UK general population. Up to five non-gout individuals were matched to each case of incident gout by year of birth, year of enrolment and body mass index (BMI). Multivariate HRs for incident diabetes were calculated after additionally adjusting for smoking, alcohol consumption, physician visits, comorbidities and medication use.

Results

Amon

SUBMITTER: Rho YH 

PROVIDER: S-EPMC4388809 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature