Ontology highlight
ABSTRACT:
SUBMITTER: Singer R
PROVIDER: S-EPMC4391747 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Science translational medicine 20120901 150
Microbicides may prevent HIV and sexually transmitted infections (STIs) in women; however, determining the optimal means of delivery of active pharmaceutical ingredients remains a major challenge. We previously demonstrated that a vaginal gel containing the non-nucleoside reverse transcriptase inhibitor MIV-150 partially protected macaques from SHIV-RT (simian/HIV reverse transcriptase) infection, and the addition of zinc acetate rendered the gel significantly protective. We test the activity of ...[more]